TIPE2 protects cardiomyocytes from ischemia-reperfusion-induced apoptosis by decreasing cell autophagy via the mTORC1 signaling pathway

In cardiac ischemia-reperfusion (I/R), autophagy of hyperactivated cardiomyocytes degrades normal proteins and organelles, destroys cells and causes irreversible cell death. The present study aimed to determine the molecular mechanism through which TNF-α-induced protein 8-like protein 2 (TIPE2) regu...

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Detalles Bibliográficos
Autores principales: Cheng, Gong, Huang, Xiaoyan, You, Penghua, Feng, Panpan, Jia, Shuo, Zhang, Ji, You, Hongjun, Chang, Fengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490124/
https://www.ncbi.nlm.nih.gov/pubmed/36160908
http://dx.doi.org/10.3892/etm.2022.11550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490124/
https://www.ncbi.nlm.nih.gov/pubmed/36160908
http://dx.doi.org/10.3892/etm.2022.11550

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