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TIPE2 protects cardiomyocytes from ischemia-reperfusion-induced apoptosis by decreasing cell autophagy via the mTORC1 signaling pathway
In cardiac ischemia-reperfusion (I/R), autophagy of hyperactivated cardiomyocytes degrades normal proteins and organelles, destroys cells and causes irreversible cell death. The present study aimed to determine the molecular mechanism through which TNF-α-induced protein 8-like protein 2 (TIPE2) regu...
Autores principales: | Cheng, Gong, Huang, Xiaoyan, You, Penghua, Feng, Panpan, Jia, Shuo, Zhang, Ji, You, Hongjun, Chang, Fengjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490124/ https://www.ncbi.nlm.nih.gov/pubmed/36160908 http://dx.doi.org/10.3892/etm.2022.11550 |
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