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The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging‐related disease
Aging represents the major risk factor for the development of cancer and many other diseases. Recent findings show that normal tissues become riddled with expanded clones that are frequently driven by cancer‐associated mutations in an aging‐dependent fashion. Additional studies show how aged tissue...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490148/ https://www.ncbi.nlm.nih.gov/pubmed/35726685 http://dx.doi.org/10.1002/1878-0261.13275 |