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Computational tumor stroma reaction evaluation led to novel prognosis-associated fibrosis and molecular signature discoveries in high-grade serous ovarian carcinoma

BACKGROUND: As one of the key criteria to differentiate benign vs. malignant tumors in ovarian and other solid cancers, tumor-stroma reaction (TSR) is long observed by pathologists and has been found correlated with patient prognosis. However, paucity of study aims to overcome subjective bias or aut...

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Detalles Bibliográficos
Autores principales: Jiang, Jun, Tekin, Burak, Yuan, Lin, Armasu, Sebastian, Winham, Stacey J., Goode, Ellen L., Liu, Hongfang, Huang, Yajue, Guo, Ruifeng, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490262/
https://www.ncbi.nlm.nih.gov/pubmed/36160147
http://dx.doi.org/10.3389/fmed.2022.994467