Nitric oxide reversibly binds the reduced [2Fe-2S] cluster in mitochondrial outer membrane protein mitoNEET and inhibits its electron transfer activity

MitoNEET is a mitochondrial outer membrane protein that regulates energy metabolism, iron homeostasis, and production of reactive oxygen species in cells. Aberrant expression of mitoNEET in tissues has been linked to type II diabetes, neurodegenerative diseases, and several types of cancer. Structur...

Descripción completa

Detalles Bibliográficos
Autores principales: Fontenot, Chelsey R., Cheng, Zishuo, Ding, Huangen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490426/
https://www.ncbi.nlm.nih.gov/pubmed/36158570
http://dx.doi.org/10.3389/fmolb.2022.995421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490426/
https://www.ncbi.nlm.nih.gov/pubmed/36158570
http://dx.doi.org/10.3389/fmolb.2022.995421

Ejemplares similares