Cargando…

Nitric oxide reversibly binds the reduced [2Fe-2S] cluster in mitochondrial outer membrane protein mitoNEET and inhibits its electron transfer activity

MitoNEET is a mitochondrial outer membrane protein that regulates energy metabolism, iron homeostasis, and production of reactive oxygen species in cells. Aberrant expression of mitoNEET in tissues has been linked to type II diabetes, neurodegenerative diseases, and several types of cancer. Structur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fontenot, Chelsey R., Cheng, Zishuo, Ding, Huangen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490426/ https://www.ncbi.nlm.nih.gov/pubmed/36158570 http://dx.doi.org/10.3389/fmolb.2022.995421

Ejemplares similares

Redox-dependent gating of VDAC by mitoNEET
por: Lipper, Colin H., et al.
Publicado: (2019)

Interactions between mitoNEET and NAF-1 in cells
por: Karmi, Ola, et al.
Publicado: (2017)

The Intriguing mitoNEET: Functional and Spectroscopic Properties of a Unique [2Fe-2S] Cluster Coordination Geometry
por: Camponeschi, Francesca, et al.
Publicado: (2022)

MitoNEET-Mediated Effects on Browning of White Adipose Tissue
por: Kusminski, Christine M., et al.
Publicado: (2014)

Electron Transfer and Proton-Coupled Electron Transfer Reactivity and Self-Exchange of Synthetic [2Fe–2S] Complexes: Models for Rieske and mitoNEET Clusters
por: Saouma, Caroline T., et al.
Publicado: (2014)

Inhibition of mitoNEET attenuates LPS-induced inflammation and oxidative stress
por: Lee, Seunghee, et al.
Publicado: (2022)

Inhibition of mitoNEET induces Pink1-Parkin-mediated mitophagy
por: Lee, Seunghee, et al.
Publicado: (2022)

The Mitochondrial Protein MitoNEET as a Probe for the Allostery of Glutamate Dehydrogenase
por: Nnatubeugo, Chimere, et al.
Publicado: (2022)

Targeting mitoNEET with pioglitazone for therapeutic neuroprotection after spinal cord injury
por: Rabchevsky, Alexander G., et al.
Publicado: (2017)

New Insights of the NEET Protein CISD2 Reveals Distinct Features Compared to Its Close Mitochondrial Homolog mitoNEET
por: Salameh, Myriam, et al.
Publicado: (2021)

Single‐Molecule Force Spectroscopy Reveals Stability of mitoNEET and its [2Fe2Se] Cluster in Weakly Acidic and Basic Solutions
por: Nie, Jing‐Yuan, et al.
Publicado: (2022)

Crystal structure of the mitochondrial protein mitoNEET bound to a benze-sulfonide ligand
por: Geldenhuys, Werner J., et al.
Publicado: (2019)

Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure
por: Furihata, Takaaki, et al.
Publicado: (2021)

MitoNEET in Perivascular Adipose Tissue Blunts Atherosclerosis under Mild Cold Condition in Mice
por: Xiong, Wenhao, et al.
Publicado: (2017)

MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk
por: Kusminski, Christine M., et al.
Publicado: (2016)

Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET
por: Huynh, Nhan, et al.
Publicado: (2019)

Multiple Poses and Thermodynamics of Ligands Targeting Protein Surfaces: The Case of Furosemide Binding to mitoNEET in Aqueous Solution
por: Hoang, Linh Gia, et al.
Publicado: (2022)

MitoNEET Protects HL-1 Cardiomyocytes from Oxidative Stress Mediated Apoptosis in an In Vitro Model of Hypoxia and Reoxygenation
por: Habener, Anika, et al.
Publicado: (2016)

Ferric uptake regulator (Fur) binds a [2Fe-2S] cluster to regulate intracellular iron homeostasis in Escherichia coli
por: Fontenot, Chelsey R., et al.
Publicado: (2023)

MicroRNA-127 targeting of mitoNEET inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection
por: He, Qin-Qin, et al.
Publicado: (2016)

Isoliquiritigenin Induces Mitochondrial Dysfunction and Apoptosis by Inhibiting mitoNEET in a Reactive Oxygen Species-Dependent Manner in A375 Human Melanoma Cells
por: Chen, Xiao-Yu, et al.
Publicado: (2019)

The long-standing relationship between paramagnetic NMR and iron–sulfur proteins: the mitoNEET example. An old method for new stories or the other way around?
por: Camponeschi, Francesca, et al.
Publicado: (2021)

Erratum: MicroRNA-127 targeting of mitoNEET inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection
por: He, Qin-Qin, et al.
Publicado: (2017)

The two redox states of the human NEET proteins’ [2Fe–2S] clusters
por: Zuo, Ke, et al.
Publicado: (2021)

Synthesis of Aminooxy Glycoside Derivatives of the Outer Core Domain of Pseudomonas aeruginosa Lipopolysaccharide
por: Si, Anshupriya, et al.
Publicado: (2021)

Kanamycin-Mediated Conformational Dynamics of Escherichia coli Outer Membrane Protein TolC
por: Pattanayak, Biraja S., et al.
Publicado: (2021)

The Role of Extracellular Loops in the Folding of Outer Membrane Protein X (OmpX) of Escherichia coli
por: Hermansen, Simen, et al.
Publicado: (2022)

Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response
por: Boos, Jacob R., et al.
Publicado: (2022)

Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis
por: Lipper, Colin H., et al.
Publicado: (2015)

Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension
por: da Silva, Mirelly Cunha, et al.
Publicado: (2022)

A Fe(2+)-dependent self-inhibited state influences the druggability of human collagen lysyl hydroxylase (LH/PLOD) enzymes
por: Scietti, Luigi, et al.
Publicado: (2022)

Absence of Cardiolipin From the Outer Leaflet of a Mitochondrial Inner Membrane Mimic Restricts Opa1-Mediated Fusion
por: Ge, Yifan, et al.
Publicado: (2021)

Interaction of client—the scaffold on which FeS clusters are build—with J-domain protein Hsc20 and its evolving Hsp70 partners
por: Marszalek, Jaroslaw, et al.
Publicado: (2022)

Low Diversity of Human Variation Despite Mostly Mild Functional Impact of De Novo Variants
por: Mahlich, Yannick, et al.
Publicado: (2021)

Insights Into Mutations Induced Conformational Changes and Rearrangement of Fe(2+) Ion in pncA Gene of Mycobacterium tuberculosis to Decipher the Mechanism of Resistance to Pyrazinamide
por: Nangraj, Asma Sindhoo, et al.
Publicado: (2021)

Molecular Dynamics Simulations of the [2Fe–2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release
por: Pesce, Luca, et al.
Publicado: (2017)

Nitric oxide-based regulation of metabolism: Hints from TRAP1 and SIRT3 crosstalk
por: Faienza, Fiorella, et al.
Publicado: (2022)

An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters
por: Marjault, Henri-Baptiste, et al.
Publicado: (2022)

A VDAC1-mediated NEET protein chain transfers [2Fe-2S] clusters between the mitochondria and the cytosol and impacts mitochondrial dynamics
por: Karmi, Ola, et al.
Publicado: (2022)

Evidence for Disruption of Mg(2+) Pair as a Resistance Mechanism Against HIV-1 Integrase Strand Transfer Inhibitors
por: Machado, Lucas de Almeida, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0fo31hkp972s2uen6mclshft9g