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Pd/Cu-catalyzed access to novel 3-(benzofuran-2-ylmethyl) substituted (pyrazolo/benzo)triazinone derivatives: their in silico/in vitro evaluation as inhibitors of chorismate mutase (CM)

In view of the reported chorismate mutase (CM or MtbCM) inhibitory activities of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives the structurally similar 3-(benzofuran-2-ylmethyl) substituted (pyrazolo/benzo)triazinones were designed and evaluated in silico against CM. The docking...

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Detalles Bibliográficos
Autores principales: Reddy, Gangireddy Sujeevan, Shukla, Sharda, Bhuktar, Harshavardhan, Hossain, Kazi Amirul, Edwin, Rebecca Kristina, Giliyaru, Varadaraj Bhat, Misra, Parimal, Pal, Manojit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490447/
https://www.ncbi.nlm.nih.gov/pubmed/36275143
http://dx.doi.org/10.1039/d2ra05255e