Haplotype-specific chromatin looping reveals genetic interactions of regulatory regions modulating gene expression in 8p23.1

A major goal of genetics research is to elucidate mechanisms explaining how genetic variation contributes to phenotypic variation. The genetic variants identified in genome-wide association studies (GWASs) generally explain only a small proportion of heritability of phenotypic traits, the so-called...

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Detalles Bibliográficos
Autores principales: Saint Just Ribeiro, Mariana, Tripathi, Pulak, Namjou, Bahram, Harley, John B., Chepelev, Iouri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490475/
https://www.ncbi.nlm.nih.gov/pubmed/36160011
http://dx.doi.org/10.3389/fgene.2022.1008582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490475/
https://www.ncbi.nlm.nih.gov/pubmed/36160011
http://dx.doi.org/10.3389/fgene.2022.1008582

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