T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer

BACKGROUND: Stimulator of interferon genes (STING) is an innate immune sensor of cytoplasmic double-stranded DNA originating from microorganisms and host cells. The activation of cytosolic DNA-STING pathway in tumor microenvironments is usually linked to more robust adaptive immune responses to tumo...

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Detalles Bibliográficos
Autores principales: Ni, Huanhe, Zhang, Huanling, Li, Lin, Huang, He, Guo, Hui, Zhang, Lin, Li, Chunwei, Xu, Jing-Xiao, Nie, Cai-Ping, Li, Kui, Zhang, Xiaoshi, Xia, Xiaojun, Li, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490630/
https://www.ncbi.nlm.nih.gov/pubmed/36126994
http://dx.doi.org/10.1136/jitc-2022-005151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490630/
https://www.ncbi.nlm.nih.gov/pubmed/36126994
http://dx.doi.org/10.1136/jitc-2022-005151

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