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T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer
BACKGROUND: Stimulator of interferon genes (STING) is an innate immune sensor of cytoplasmic double-stranded DNA originating from microorganisms and host cells. The activation of cytosolic DNA-STING pathway in tumor microenvironments is usually linked to more robust adaptive immune responses to tumo...
Autores principales: | Ni, Huanhe, Zhang, Huanling, Li, Lin, Huang, He, Guo, Hui, Zhang, Lin, Li, Chunwei, Xu, Jing-Xiao, Nie, Cai-Ping, Li, Kui, Zhang, Xiaoshi, Xia, Xiaojun, Li, Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490630/ https://www.ncbi.nlm.nih.gov/pubmed/36126994 http://dx.doi.org/10.1136/jitc-2022-005151 |
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