Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension

[Image: see text] Albumin-binding fusion partners are frequently used as a means for the in vivo half-life extension of small therapeutic molecules that would normally be cleared very rapidly from circulation. However, in applications where small size is key, fusion to an additional molecule can be...

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Detalles Bibliográficos
Autores principales: von Witting, Emma, Lindbo, Sarah, Lundqvist, Magnus, Möller, Marit, Wisniewski, Andreas, Kanje, Sara, Rockberg, Johan, Tegel, Hanna, Åstrand, Mikael, Uhlén, Mathias, Hober, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490751/
https://www.ncbi.nlm.nih.gov/pubmed/33259222
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490751/
https://www.ncbi.nlm.nih.gov/pubmed/33259222
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00975

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