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Multiple pore lining residues modulate water permeability of GlpF

The water permeability of aquaporins (AQPs) varies by more than an order of magnitude even though the pore structure, geometry, as well as the channel lining residues are highly conserved. However, channel gating by pH, divalent ions or phosphorylation was only shown for a minority of AQPs. Structur...

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Detalles Bibliográficos
Autores principales: Pluhackova, Kristyna, Schittny, Valentin, Bürkner, Paul‐Christian, Siligan, Christine, Horner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490802/
https://www.ncbi.nlm.nih.gov/pubmed/36173178
http://dx.doi.org/10.1002/pro.4431