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Nanoscale alterations in GABA(B) receptors and GIRK channel organization on the hippocampus of APP/PS1 mice

Alzheimer’s disease (AD) is characterized by a reorganization of brain activity determining network hyperexcitability and loss of synaptic plasticity. Precisely, a dysfunction in metabotropic GABA(B) receptor signalling through G protein-gated inwardly rectifying K(+) (GIRK or Kir3) channels on the...

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Detalles Bibliográficos
Autores principales: Martín-Belmonte, Alejandro, Aguado, Carolina, Alfaro-Ruiz, Rocío, Moreno-Martínez, Ana Esther, de la Ossa, Luis, Aso, Ester, Gómez-Acero, Laura, Shigemoto, Ryuichi, Fukazawa, Yugo, Ciruela, Francisco, Luján, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490896/
https://www.ncbi.nlm.nih.gov/pubmed/36131327
http://dx.doi.org/10.1186/s13195-022-01078-5