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Four methylation-driven genes detected by linear discriminant analysis model from early-stage colorectal cancer and their methylation levels in cell-free DNA

The process of colorectal cancer (CRC) formation is considered a typical model of multistage carcinogenesis in which aberrant DNA methylation plays an important role. In this study, 752 methylation-driven genes (MDGs) were identified by the MethylMix package based on methylation and gene expression...

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Detalles Bibliográficos
Autores principales: Zhan, Lei, Sun, Changjian, Zhang, Yu, Zhang, Yue, Jia, Yuzhe, Wang, Xiaoyan, Li, Feifei, Li, Donglin, Wang, Shen, Yu, Tao, Zhang, Jingdong, Li, Deyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491101/
https://www.ncbi.nlm.nih.gov/pubmed/36158666
http://dx.doi.org/10.3389/fonc.2022.949244