Oral administration of a dual ET(A)/ET(B) receptor antagonist promotes neuroprotection in a rodent model of glaucoma

PURPOSE: Glaucoma is a neurodegenerative disease associated with elevated intraocular pressure and characterized by optic nerve axonal degeneration, cupping of the optic disc, and loss of retinal ganglion cells (RGCs). The endothelin (ET) system of vasoactive peptides (ET-1, ET-2, ET-3) and their G-...

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Detalles Bibliográficos
Autores principales: Kodati, Bindu, McGrady, Nolan R., Jefferies, Hayden B., Stankowska, Dorota L., Krishnamoorthy, Raghu R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491150/
https://www.ncbi.nlm.nih.gov/pubmed/36274816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491150/
https://www.ncbi.nlm.nih.gov/pubmed/36274816

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