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Rational development of molecularly imprinted nanoparticles for blocking PD-1/PD-L1 axis

Blocking the PD-1/PD-L1 immune checkpoint has emerged as a promising strategy in cancer immunotherapy, in which monoclonal antibodies are predominately used as inhibitors. Despite their remarkable success, monoclonal antibody-based therapeutics suffer from drawbacks due to the use of antibodies, suc...

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Detalles Bibliográficos
Autores principales: Gu, Zikuan, Xu, Shuxin, Guo, Zhanchen, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491213/
https://www.ncbi.nlm.nih.gov/pubmed/36320712
http://dx.doi.org/10.1039/d2sc03412c