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HIV-1 Vpr suppresses expression of the thiazide-sensitive sodium chloride co-transporter in the distal convoluted tubule

HIV-associated nephropathy (HIVAN) impairs functions of both glomeruli and tubules. Attention has been previously focused on the HIVAN glomerulopathy. Tubular injury has drawn increased attention because sodium wasting is common in hospitalized HIV/AIDS patients. We used viral protein R (Vpr)-transg...

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Detalles Bibliográficos
Autores principales: Shrivastav, Shashi, Lee, Hewang, Okamoto, Koji, Lu, Huiyan, Yoshida, Teruhiko, Latt, Khun Zaw, Wakashin, Hidefumi, Dalgleish, James L. T., Koritzinsky, Erik H., Xu, Peng, Asico, Laureano D., Chung, Joon-Yong, Hewitt, Stephen, Gildea, John J., Felder, Robin A., Jose, Pedro A., Rosenberg, Avi Z., Knepper, Mark A., Kino, Tomoshige, Kopp, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491550/
https://www.ncbi.nlm.nih.gov/pubmed/36129874
http://dx.doi.org/10.1371/journal.pone.0273313