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Psychosocial stress and cannabinoid drugs affect acetylation of α-tubulin (K40) and gene expression in the prefrontal cortex of adult mice

The dynamics of neuronal microtubules are essential for brain plasticity. Vesicular transport and synaptic transmission, additionally, requires acetylation of α-tubulin, and aberrant tubulin acetylation and neurobiological deficits are associated. Prolonged exposure to a stressor or consumption of d...

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Detalles Bibliográficos
Autores principales: Tomas-Roig, Jordi, Ramasamy, Shyam, Zbarsky, Diana, Havemann-Reinecke, Ursula, Hoyer-Fender, Sigrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491557/
https://www.ncbi.nlm.nih.gov/pubmed/36129937
http://dx.doi.org/10.1371/journal.pone.0274352