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Quantitative prediction of ensemble dynamics, shapes and contact propensities of intrinsically disordered proteins

Intrinsically disordered proteins (IDPs) are highly dynamic systems that play an important role in cell signaling processes and their misfunction often causes human disease. Proper understanding of IDP function not only requires the realistic characterization of their three-dimensional conformationa...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Brüschweiler, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491582/
https://www.ncbi.nlm.nih.gov/pubmed/36084124
http://dx.doi.org/10.1371/journal.pcbi.1010036