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A transcriptional cycling model recapitulates chromatin-dependent features of noisy inducible transcription
Activation of gene expression in response to environmental cues results in substantial phenotypic heterogeneity between cells that can impact a wide range of outcomes including differentiation, viral activation, and drug resistance. An important source of gene expression noise is transcriptional bur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491597/ https://www.ncbi.nlm.nih.gov/pubmed/36084132 http://dx.doi.org/10.1371/journal.pcbi.1010152 |