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A transcriptional cycling model recapitulates chromatin-dependent features of noisy inducible transcription

Activation of gene expression in response to environmental cues results in substantial phenotypic heterogeneity between cells that can impact a wide range of outcomes including differentiation, viral activation, and drug resistance. An important source of gene expression noise is transcriptional bur...

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Detalles Bibliográficos
Autores principales: Bullock, M. Elise, Moreno-Martinez, Nataly, Miller-Jensen, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491597/
https://www.ncbi.nlm.nih.gov/pubmed/36084132
http://dx.doi.org/10.1371/journal.pcbi.1010152