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Label-free hyperspectral imaging and deep-learning prediction of retinal amyloid β-protein and phosphorylated tau

Alzheimer’s disease (AD) is a major risk for the aging population. The pathological hallmarks of AD—an abnormal deposition of amyloid β-protein (Aβ) and phosphorylated tau (pTau)—have been demonstrated in the retinas of AD patients, including in prodromal patients with mild cognitive impairment (MCI...

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Detalles Bibliográficos
Autores principales: Du, Xiaoxi, Koronyo, Yosef, Mirzaei, Nazanin, Yang, Chengshuai, Fuchs, Dieu-Trang, Black, Keith L, Koronyo-Hamaoui, Maya, Gao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491695/
https://www.ncbi.nlm.nih.gov/pubmed/36157597
http://dx.doi.org/10.1093/pnasnexus/pgac164