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Aminoacyl transfer ribonucleic acid synthetase complex-interacting multifunctional protein 1 induces microglial activation and M1 polarization via the mitogen-activated protein kinase/nuclear factor-kappa B signaling pathway

Activation of microglia, which is the primary immune cell of the central nervous system, plays an important role in neuroinflammation associated with several neuronal diseases. Aminoacyl tRNA synthetase (ARS) complex-interacting multifunctional protein 1 (AIMP1), a structural component of the multie...

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Detalles Bibliográficos
Autores principales: Oh, Yebin, Jung, Hak-Jun, Hong, Seungwon, Cho, Yerim, Park, Jiyeong, Cho, Daeho, Kim, Tae Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491728/
https://www.ncbi.nlm.nih.gov/pubmed/36159396
http://dx.doi.org/10.3389/fncel.2022.977205