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powerEQTL: an R package and shiny application for sample size and power calculation of bulk tissue and single-cell eQTL analysis

SUMMARY: Genome-wide association studies (GWAS) have revealed thousands of genetic loci for common diseases. One of the main challenges in the post-GWAS era is to understand the causality of the genetic variants. Expression quantitative trait locus (eQTL) analysis is an effective way to address this...

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Detalles Bibliográficos
Autores principales: Dong, Xianjun, Li, Xiaoqi, Chang, Tzuu-Wang, Scherzer, Clemens R, Weiss, Scott T, Qiu, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492284/
https://www.ncbi.nlm.nih.gov/pubmed/34009297
http://dx.doi.org/10.1093/bioinformatics/btab385