Quantification of Viral RNA in Multiple Pieces of Explant Liver Tissue Shows Distinct Focal Differences in Hepatitis B Infection( )

Hepatitis B virus (HBV) DNA and RNA were quantified by digital PCR assays in 20–30 tissue pieces from each of 4 liver explants with cirrhosis caused by HBV. The within-patient variability of HBV RNA levels between pieces was up to a 1000-fold. Core RNA and S RNA levels were similar and correlated st...

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Detalles Bibliográficos
Autores principales: Rydell, Gustaf E, Prakash, Kasthuri, Larsson, Simon B, Skoglund, Catarina, Ringlander, Johan, Andersson, Maria E, Castedal, Maria, Norder, Heléne, Lindh, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492311/
https://www.ncbi.nlm.nih.gov/pubmed/34534318
http://dx.doi.org/10.1093/infdis/jiab469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492311/
https://www.ncbi.nlm.nih.gov/pubmed/34534318
http://dx.doi.org/10.1093/infdis/jiab469

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