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Quantification of Viral RNA in Multiple Pieces of Explant Liver Tissue Shows Distinct Focal Differences in Hepatitis B Infection( )
Hepatitis B virus (HBV) DNA and RNA were quantified by digital PCR assays in 20–30 tissue pieces from each of 4 liver explants with cirrhosis caused by HBV. The within-patient variability of HBV RNA levels between pieces was up to a 1000-fold. Core RNA and S RNA levels were similar and correlated st...
Autores principales: | Rydell, Gustaf E, Prakash, Kasthuri, Larsson, Simon B, Skoglund, Catarina, Ringlander, Johan, Andersson, Maria E, Castedal, Maria, Norder, Heléne, Lindh, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492311/ https://www.ncbi.nlm.nih.gov/pubmed/34534318 http://dx.doi.org/10.1093/infdis/jiab469 |
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