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Malignant clonal evolution drives multiple myeloma cellular ecological diversity and microenvironment reprogramming
BACKGROUND: Multiple myeloma (MM) is a heterogeneous disease with different patterns of clonal evolution and a complex tumor microenvironment, representing a challenge for clinicians and pathologists to understand and dissect the contribution and impact of polyclonality on tumor progression. METHODS...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492468/ https://www.ncbi.nlm.nih.gov/pubmed/36131282 http://dx.doi.org/10.1186/s12943-022-01648-z |