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Malignant clonal evolution drives multiple myeloma cellular ecological diversity and microenvironment reprogramming

BACKGROUND: Multiple myeloma (MM) is a heterogeneous disease with different patterns of clonal evolution and a complex tumor microenvironment, representing a challenge for clinicians and pathologists to understand and dissect the contribution and impact of polyclonality on tumor progression. METHODS...

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Detalles Bibliográficos
Autores principales: Liang, Yuanzheng, He, Haiyan, Wang, Weida, Wang, Henan, Mo, Shaowen, Fu, Ruiying, Liu, Xindi, Song, Qiong, Xia, Zhongjun, Wang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492468/
https://www.ncbi.nlm.nih.gov/pubmed/36131282
http://dx.doi.org/10.1186/s12943-022-01648-z