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Relaxin does not prevent development of hypoxia-induced pulmonary edema in rats

Acute hypoxia impairs left ventricular (LV) inotropic function and induces development of pulmonary edema (PE). Enhanced and uneven hypoxic pulmonary vasoconstriction is an important pathogenic factor of hypoxic PE. We hypothesized that the potent vasodilator relaxin might reduce hypoxic pulmonary v...

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Detalles Bibliográficos
Autores principales: Kowalleck, Ute, Ahmed, Mohamed A. Abdalla, Koedel, Julia, Schierle, Katrin, Salameh, Aida, Rassler, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492557/
https://www.ncbi.nlm.nih.gov/pubmed/35778581
http://dx.doi.org/10.1007/s00424-022-02720-9