Prostate tumor RON receptor signaling mediates macrophage recruitment to drive androgen deprivation therapy resistance through Gas6‐mediated Axl and RON signaling

BACKGROUND: Androgen deprivation therapy (ADT), or chemical castration, is the first‐line therapy for prostate cancer; however, resistance leaves few treatment options. Prostatic tumor‐associated macrophages (TAMs) have been shown to promote prostate cancer growth and are abundant in castration‐resi...

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Detalles Bibliográficos
Autores principales: Brown, Nicholas E., Jones, Angelle, Hunt, Brian G., Waltz, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492645/
https://www.ncbi.nlm.nih.gov/pubmed/35860905
http://dx.doi.org/10.1002/pros.24416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492645/
https://www.ncbi.nlm.nih.gov/pubmed/35860905
http://dx.doi.org/10.1002/pros.24416

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