The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T-cell recognition

Although the Omicron variant of the SARS-CoV-2 virus shows resistance to neutralizing antibody, it retains susceptibility to the cellular immune response. Here we characterize vaccine-induced T cells specific for various SARS-CoV-2 variants and identified HLA-A*24:02-restricted CD8(+) T cells that s...

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Detalles Bibliográficos
Autores principales: Motozono, Chihiro, Toyoda, Mako, Tan, Toong Seng, Hamana, Hiroshi, Goto, Yoshihiko, Aritsu, Yoshiki, Miyashita, Yusuke, Oshiumi, Hiroyuki, Nakamura, Kimitoshi, Okada, Seiji, Udaka, Keiko, Kitamatsu, Mizuki, Kishi, Hiroyuki, Ueno, Takamasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492656/
https://www.ncbi.nlm.nih.gov/pubmed/36130929
http://dx.doi.org/10.1038/s41467-022-33068-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492656/
https://www.ncbi.nlm.nih.gov/pubmed/36130929
http://dx.doi.org/10.1038/s41467-022-33068-4

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