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The conservation of human functional variants and their effects across livestock species

Despite the clear potential of livestock models of human functional variants to provide important insights into the biological mechanisms driving human diseases and traits, their use to date has been limited. Generating such models via genome editing is costly and time consuming, and it is unclear w...

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Detalles Bibliográficos
Autores principales: Zhao, Rongrong, Talenti, Andrea, Fang, Lingzhao, Liu, Shuli, Liu, George, Chue Hong, Neil P., Tenesa, Albert, Hassan, Musa, Prendergast, James G. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492664/
https://www.ncbi.nlm.nih.gov/pubmed/36131008
http://dx.doi.org/10.1038/s42003-022-03961-1