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Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish

Clockwise rotation of the primitive heart tube, a process regulated by restricted left-sided Nodal signaling, is the first morphological manifestation of left-right asymmetry. How Nodal regulates cell behaviors to drive asymmetric morphogenesis remains poorly understood. Here, using high-resolution...

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Detalles Bibliográficos
Autores principales: Kidokoro, Hinako, Saijoh, Yukio, Schoenwolf, Gary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492702/
https://www.ncbi.nlm.nih.gov/pubmed/36131094
http://dx.doi.org/10.1038/s42003-022-03826-7