Heparanase modulates the prognosis and development of BRAF V600E-mutant colorectal cancer by regulating AKT/p27Kip1/Cyclin E2 pathway

BRAF V600E-mutant colorectal cancer (CRC) is a rare subtype of colorectal cancer with poor prognosis. Compelling evidence indicates that the heparanase (HPSE) gene has multiple functions in cancer, however, its role in BRAF V600E-mutant CRC remains elusive. Differentially expressed genes between BRA...

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Detalles Bibliográficos
Autores principales: Liu, Mengling, Xu, Xiaojing, Peng, Ke, Hou, Pengcong, Yuan, Yitao, Li, Suyao, Sun, Xun, Shi, Zhongyi, Zhang, Jiayu, Dong, Yu, Liu, Qing, Ai, Luoyan, Liang, Li, Gan, Lu, Huang, Qihong, Yu, Yiyi, Liu, Tianshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492760/
https://www.ncbi.nlm.nih.gov/pubmed/36130926
http://dx.doi.org/10.1038/s41389-022-00428-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492760/
https://www.ncbi.nlm.nih.gov/pubmed/36130926
http://dx.doi.org/10.1038/s41389-022-00428-0

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