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Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency

The support of pluripotent cells over time is an essential feature of development. In eutherian embryos, pluripotency is maintained from naïve states in peri-implantation to primed pluripotency at gastrulation. To understand how these states emerged, we reconstruct the evolutionary trajectory of the...

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Detalles Bibliográficos
Autores principales: Sukparangsi, Woranop, Morganti, Elena, Lowndes, Molly, Mayeur, Hélène, Weisser, Melanie, Hammachi, Fella, Peradziryi, Hanna, Roske, Fabian, Hölzenspies, Jurriaan, Livigni, Alessandra, Godard, Benoit Gilbert, Sugahara, Fumiaki, Kuratani, Shigeru, Montoya, Guillermo, Frankenberg, Stephen R., Mazan, Sylvie, Brickman, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492771/
https://www.ncbi.nlm.nih.gov/pubmed/36130934
http://dx.doi.org/10.1038/s41467-022-32481-z