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Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models

Maternal obesity during pregnancy is associated with neurodevelopmental disorder (NDD) risk. We utilized integrative multi-omics to examine maternal obesity effects on offspring neurodevelopment in rhesus macaques by comparison to lean controls and two interventions. Differentially methylated region...

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Detalles Bibliográficos
Autores principales: Laufer, Benjamin I., Hasegawa, Yu, Zhang, Zhichao, Hogrefe, Casey E., Del Rosso, Laura A., Haapanen, Lori, Hwang, Hyeyeon, Bauman, Melissa D., Van de Water, Judy, Taha, Ameer Y., Slupsky, Carolyn M., Golub, Mari S., Capitanio, John P., VandeVoort, Catherine A., Walker, Cheryl K., LaSalle, Janine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492781/
https://www.ncbi.nlm.nih.gov/pubmed/36130949
http://dx.doi.org/10.1038/s41467-022-33162-7