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Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models
Maternal obesity during pregnancy is associated with neurodevelopmental disorder (NDD) risk. We utilized integrative multi-omics to examine maternal obesity effects on offspring neurodevelopment in rhesus macaques by comparison to lean controls and two interventions. Differentially methylated region...
Autores principales: | Laufer, Benjamin I., Hasegawa, Yu, Zhang, Zhichao, Hogrefe, Casey E., Del Rosso, Laura A., Haapanen, Lori, Hwang, Hyeyeon, Bauman, Melissa D., Van de Water, Judy, Taha, Ameer Y., Slupsky, Carolyn M., Golub, Mari S., Capitanio, John P., VandeVoort, Catherine A., Walker, Cheryl K., LaSalle, Janine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492781/ https://www.ncbi.nlm.nih.gov/pubmed/36130949 http://dx.doi.org/10.1038/s41467-022-33162-7 |
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