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High Expression of the Costimulatory Checkpoint Factor DNAM-1 by CD4(+) T-Cells from Multiple Myeloma Patients Refractory to Daratumumab-Containing Regimens

Multiple myeloma is an incurable disease characterized by unregulated growth of malignant plasma cells in the bone marrow (BM). Tumor-induced dysfunction of T-cells may be responsible for immune evasion and failure of immunotherapy. Therefore, a better understanding of the phenotype of T-cells at th...

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Detalles Bibliográficos
Autores principales: Iversen, Katrine Fladeland, Nederby, Line, Lund, Thomas, Plesner, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492812/
https://www.ncbi.nlm.nih.gov/pubmed/36131131
http://dx.doi.org/10.1007/s44228-022-00013-7