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ELA-11 protects the heart against oxidative stress injury induced apoptosis through ERK/MAPK and PI3K/AKT signaling pathways

Increasing evidence revealed that apoptosis and oxidative stress injury were associated with the pathophysiology of doxorubicin (DOX)-induced myocardial injury. ELABELA (ELA) is a newly identified peptide with 32 amino acids, can reduce hypertension with exogenous infusion. However, the effect of 11...

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Detalles Bibliográficos
Autores principales: Wang, Xuejun, Zhang, Li, Feng, Mengwen, Xu, Zhongqing, Cheng, Zijie, Qian, Lingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492932/
https://www.ncbi.nlm.nih.gov/pubmed/36160397
http://dx.doi.org/10.3389/fphar.2022.873614