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Five decades of clinical assessment of whole-sporozoite malaria vaccines
In 1967, pioneering work by Ruth Nussenzweig demonstrated for the first time that irradiated sporozoites of the rodent malaria parasite Plasmodium berghei protected mice against a challenge with infectious parasites of the same species. This remarkable finding opened up entirely new prospects of eff...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493004/ https://www.ncbi.nlm.nih.gov/pubmed/36159849 http://dx.doi.org/10.3389/fimmu.2022.977472 |