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Transformation of adenocarcinoma to squamous cell carcinoma as a source of EGFR-TKI resistance: A case report and literature review

In general, non-small cell lung cancer patients with epidermal growth factor receptor (EGFR) mutations respond to tyrosine kinase inhibitors (TKIs). However, most patients experience resistance within 1-2 years after treatment. The histological explanation for the acquired resistance is that maligna...

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Detalles Bibliográficos
Autores principales: Xi, Yun-Zhu, Xie, Li, Tan, Xiao-Wu, Zeng, Sai-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493008/
https://www.ncbi.nlm.nih.gov/pubmed/36158654
http://dx.doi.org/10.3389/fonc.2022.942084