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Combined – whole blood and skin fibroblasts- transcriptomic analysis in Psoriatic Arthritis reveals molecular signatures of activity, resistance and early response to treatment

BACKGROUND: An interplay between immune cells and resident skin and joint stromal cells is implicated in psoriatic arthritis (PsA), yet the mechanisms remain elusive with a paucity of molecular biomarkers for activity and response. Combined transcriptomic and immunophenotypic analysis of whole blood...

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Detalles Bibliográficos
Autores principales: Grivas, Alexandros, Grigoriou, Maria, Malissovas, Nikos, Sentis, George, Filia, Anastasia, Flouda, Sofia, Katsimpri, Pelagia, Verginis, Panayotis, Boumpas, Dimitrios T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493103/
https://www.ncbi.nlm.nih.gov/pubmed/36159832
http://dx.doi.org/10.3389/fimmu.2022.964274