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Caloric restriction prevents obesity- and intermittent hypoxia-induced cardiac remodeling in leptin-deficient ob/ob mice
Background: Intermittent hypoxia (IH), a key characteristic of obstructive sleep apnea, is independently associated with cardiometabolic impairment. While endogenous leptin levels may provide cardioprotective effects against hypoxia, leptin resistance is common among obese individuals presenting wit...
Autores principales: | Jones, Aaron A., Framnes-DeBoer, Sarah N., Shipp, Arianne, Arble, Deanna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493268/ https://www.ncbi.nlm.nih.gov/pubmed/36160851 http://dx.doi.org/10.3389/fphys.2022.963762 |
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