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Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions

INTRODUCTION: Human induced pluripotent stem cells (hiPSCs) are generated through the reprogramming of somatic cells expressing a defined set of transcription factors. The advent of autologous iPSCs has enabled the generation of patient-specific iPSC lines and is expected to contribute to the explor...

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Detalles Bibliográficos
Autores principales: Morita, Kazuki, Nakamura, Akihiro, Machida, Masakazu, Kawasaki, Tomoyuki, Nakanishi, Rina, Ichida, Justin, Iwata, Takanori, Umezawa, Akihiro, Akutsu, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493288/
https://www.ncbi.nlm.nih.gov/pubmed/36196449
http://dx.doi.org/10.1016/j.reth.2022.09.002