N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase

Trypanosomes cause the devastating disease trypanosomiasis, in which the action of trans-sialidase (TS) enzymes harbored on their surface is a key virulence factor. TS enzymes are N-glycosylated, but the biological functions of their glycans have remained elusive. In this study, we investigated the...

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Detalles Bibliográficos
Autores principales: Rosenau, Jana, Grothaus, Isabell Louise, Yang, Yikun, Kumar, Nilima Dinesh, Ciacchi, Lucio Colombi, Kelm, Sørge, Waespy, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493392/
https://www.ncbi.nlm.nih.gov/pubmed/35995210
http://dx.doi.org/10.1016/j.jbc.2022.102403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493392/
https://www.ncbi.nlm.nih.gov/pubmed/35995210
http://dx.doi.org/10.1016/j.jbc.2022.102403

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