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N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase
Trypanosomes cause the devastating disease trypanosomiasis, in which the action of trans-sialidase (TS) enzymes harbored on their surface is a key virulence factor. TS enzymes are N-glycosylated, but the biological functions of their glycans have remained elusive. In this study, we investigated the...
Autores principales: | Rosenau, Jana, Grothaus, Isabell Louise, Yang, Yikun, Kumar, Nilima Dinesh, Ciacchi, Lucio Colombi, Kelm, Sørge, Waespy, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493392/ https://www.ncbi.nlm.nih.gov/pubmed/35995210 http://dx.doi.org/10.1016/j.jbc.2022.102403 |
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