Activation of TRPV4 by lactate as a critical mediator of renal fibrosis in spontaneously hypertensive rats after moderate- and high-intensity exercise

Moderate-intensity exercise training has been regarded a healthy way to alleviate kidney fibrosis by the transforming growth factor-beta (TGFβ) signaling pathway. However, the impact of different intensity exercise training on renal function is unknown, and the underlying mechanism is also unclear....

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Detalles Bibliográficos
Autores principales: Zhao, Binyi, Xu, Yanping, Chen, Yunlin, Cai, Ying, Gong, Zhiyan, Li, Dan, Kuang, Hongyu, Liu, Xiaozhu, Zhou, Hao, Liu, Guochun, Yin, Yuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493464/
https://www.ncbi.nlm.nih.gov/pubmed/36160854
http://dx.doi.org/10.3389/fphys.2022.927078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493464/
https://www.ncbi.nlm.nih.gov/pubmed/36160854
http://dx.doi.org/10.3389/fphys.2022.927078

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