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Activation of TRPV4 by lactate as a critical mediator of renal fibrosis in spontaneously hypertensive rats after moderate- and high-intensity exercise
Moderate-intensity exercise training has been regarded a healthy way to alleviate kidney fibrosis by the transforming growth factor-beta (TGFβ) signaling pathway. However, the impact of different intensity exercise training on renal function is unknown, and the underlying mechanism is also unclear....
Autores principales: | Zhao, Binyi, Xu, Yanping, Chen, Yunlin, Cai, Ying, Gong, Zhiyan, Li, Dan, Kuang, Hongyu, Liu, Xiaozhu, Zhou, Hao, Liu, Guochun, Yin, Yuehui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493464/ https://www.ncbi.nlm.nih.gov/pubmed/36160854 http://dx.doi.org/10.3389/fphys.2022.927078 |
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