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Reconstructing cancer phylogenies using Pairtree, a clone tree reconstruction algorithm

Pairtree is a clone tree reconstruction algorithm that uses somatic point mutations to build clone trees describing the evolutionary history of individual cancers. Using the Pairtree software package, we describe steps to preprocess somatic mutation data, cluster mutations into subclones, search for...

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Detalles Bibliográficos
Autores principales: Kulman, Ethan, Wintersinger, Jeff, Morris, Quaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494285/
https://www.ncbi.nlm.nih.gov/pubmed/36129821
http://dx.doi.org/10.1016/j.xpro.2022.101706