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Reconstructing cancer phylogenies using Pairtree, a clone tree reconstruction algorithm
Pairtree is a clone tree reconstruction algorithm that uses somatic point mutations to build clone trees describing the evolutionary history of individual cancers. Using the Pairtree software package, we describe steps to preprocess somatic mutation data, cluster mutations into subclones, search for...
Autores principales: | Kulman, Ethan, Wintersinger, Jeff, Morris, Quaid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494285/ https://www.ncbi.nlm.nih.gov/pubmed/36129821 http://dx.doi.org/10.1016/j.xpro.2022.101706 |
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