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Polymer-tethered glycosylated gold nanoparticles recruit sialylated glycoproteins into their protein corona, leading to off-target lectin binding

Upon exposure to biological fluids, the fouling of nanomaterial surfaces results in non-specific capture of proteins, which is particularly important when in contact with blood for in vivo and ex vivo applications. It is crucial to evaluate not just the protein components but also the glycans attach...

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Detalles Bibliográficos
Autores principales: Ahmad, Ashfaq, Georgiou, Panagiotis G., Pancaro, Alessia, Hasan, Muhammad, Nelissen, Inge, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494357/
https://www.ncbi.nlm.nih.gov/pubmed/36053227
http://dx.doi.org/10.1039/d2nr01818g