Synthesis and Molecular Docking Study of New Thiazole Derivatives as Potential Tubulin Polymerization Inhibitors

[Image: see text] A new series of 2,4-disubstituted thiazole derivatives containing 4-(3,4,5-trimethoxyphenyl) moiety was synthesized and evaluated for their potential anticancer activity as tubulin polymerization inhibitors. All designed compounds were screened for cytotoxic activity against four h...

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Detalles Bibliográficos
Autores principales: El-Abd, Azhar O., Bayomi, Said M., El-Damasy, Ashraf K., Mansour, Basem, Abdel-Aziz, Naglaa I., El-Sherbeny, Magda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494671/
https://www.ncbi.nlm.nih.gov/pubmed/36157722
http://dx.doi.org/10.1021/acsomega.2c05077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494671/
https://www.ncbi.nlm.nih.gov/pubmed/36157722
http://dx.doi.org/10.1021/acsomega.2c05077

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